08/06/2020
Research Article
Mapping gene flow between ancient hominins through demography-aware inference of the ancestral recombination graph
Here, Hubisz et al present ARGweaver-D, an extension of the ARGweaver algorithm which can be applied under a user-defined demographic model including population splits and migration events. Using simulations, the authors identify 3% of the Neanderthal genome which is likely derived from gene flow from ancient humans, and 1% of the Denisovan genome that may be traced to an unsequenced archaic hominin.
Image credit: Hubisz and colleagues
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