Biological techniques

Biological techniques are methods or procedures that are used to study living things. They include experimental and computational methods, approaches, protocols and tools for biological research.

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Latest Research and Reviews

  • Research
    | Open Access

    • Emilio J. González-Ramírez
    • , Aritz B. García-Arribas
    • , Jesús Sot
    • , Félix M. Goñi
    •  & Alicia Alonso
    Scientific Reports 10, 14085

  • Research
    | Open Access

    • Benoît X. E. Desbiolles
    • , Etienne de Coulon
    • , Nicolas Maïno
    • , Arnaud Bertsch
    • , Stephan Rohr
    •  & Philippe Renaud
    Microsystems & Nanoengineering 6, 67

  • Research |

    Cyclic β-amino acids can add useful properties to peptides, such as inducing turn structures or providing resistance to proteases. To harness these properties up to ten consecutive cyclic β-amino acids have now been ribosomally incorporated via genetic code reprogramming into a foldamer peptide library that has been screened for potent binders against a protein target, human factor XIIa.

    • Takayuki Katoh
    • , Toru Sengoku
    • , Kunio Hirata
    • , Kazuhiro Ogata
    •  & Hiroaki Suga
    Nature Chemistry, 1-8

  • Research |

    The authors infer that pelvic skeleton reduction in a fossil sequence of the Miocene stickleback fish, Gasterosteus doryssus, proceeds through the same gene of large effect and a similar suite of genes of small effect as in a closely related extant species, Gasterosteus aculeatus.

    • Yoel E. Stuart
    • , Matthew P. Travis
    •  & Michael A. Bell
    Nature Ecology & Evolution, 1-9

  • Research
    | Open Access

    • Xianmei Yin
    • , Shuai Guo
    • , Jihai Gao
    • , Lu Luo
    • , Xuejiao Liao
    • , Mingqian Li
    • , He Su
    • , Zhihai Huang
    • , Jiang Xu
    • , Jin Pei
    •  & Shilin Chen
    Scientific Reports 10, 14142
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News and Comment

  • News and Views |

    Meta-analysis of four human cohort studies reveals specific keystone bacteria associated with gut microbiome recovery after antibiotic exposure.

    • Sean M. Gibbons
    Nature Microbiology 5, 1067-1068

  • Comments and Opinion |

    To celebrate the first 20 years of Nature Reviews Genetics, we asked 12 leading scientists to reflect on the key challenges and opportunities faced by the field of genetics and genomics.

    • Amy L. McGuire
    • , Stacey Gabriel
    • , Sarah A. Tishkoff
    • , Ambroise Wonkam
    • , Aravinda Chakravarti
    • , Eileen E. M. Furlong
    • , Barbara Treutlein
    • , Alexander Meissner
    • , Howard Y. Chang
    • , Núria López-Bigas
    • , Eran Segal
    •  & Jin-Soo Kim
    Nature Reviews Genetics, 1-16

  • News and Views |

    A new cryo-EM structure of mitochondrial complex I reveals ordered water molecules that connect key elements of the proton-translocating machinery. Analysis of the ubiquinone-binding site of complex I offers insights into the mechanism of catalytic turnover and the regulation of this essential metabolic enzyme.

    • Alexander Galkin
    Nature Structural & Molecular Biology, 1-3

  • Research Highlights |

    A recent study combines CRISPR-based perturbation with single-cell RNA sequencing to characterize the roles of epigenome regulator proteins in controlling cell fate and identity during embryonic development.

    • Darren J. Burgess
    Nature Reviews Genetics, 1
All News & Comment