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Case Reports
. 2004 Dec;19(12):3180-2.
doi: 10.1093/ndt/gfh436.

Acute renal failure in SARS patients: more than rhabdomyolysis

Vin-Cent Wu  1 , Po-Ren Hsueh, Wei-Chou Lin, Jenq-Wen Huang, Hung-Bin Tsai, Yung-Ming Chen, Kwan-Dun Wu, SARS Research Group of the National Taiwan University College of Medicine and National University Hospital
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Acute renal failure in SARS patients: more than rhabdomyolysis

Vin-Cent Wu et al. Nephrol Dial Transplant. .
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Figures

Fig. 1.
(a) The kidney from case 1. The renal tubule showed prominent cytoplasmic wasting pigment deposition with lymphocytes. The casts in the tubules (arrow) are positive for myoglobin (immunohistochemical stain, 200×). (b) The skeletal muscles from case 2. Myoid giant cells (white arrow) and interstitial ecstatic lymphovascular structures with inflammatory cell infiltration are evident (HE stain, 100×). (c) The kidney from case 2. There are several Mallory body-like casts (arrowhead) in dilated lumens with some sloughed and flattened renal tubular epithelial cells, indicating rhabdomyolysis and acute tubular necrosis. Interstitial infiltration of mononuclear cells is evident. There was a mild increase in mesangial cellularity and matrix (HE, 200×). (d) The glomerulus of case 2 (electron microscopy). Intact basement membrane surrounded by podocytes (×11 500). There was no immune complex deposition or virus particles.
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References

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