doi: 10.1038/nbt.2473.
Human embryonic stem cells commonly display large mitochondrial DNA deletions
- PMID: 23302926
- DOI: 10.1038/nbt.2473
Item in Clipboard
Human embryonic stem cells commonly display large mitochondrial DNA deletions
Nat Biotechnol.
.
No abstract available
Similar articles
-
Analysis of Mitochondrial DNA in Induced Pluripotent and Embryonic Stem Cells.Methods Mol Biol. 2015;1330:219-52. doi: 10.1007/978-1-4939-2848-4_18. Methods Mol Biol. 2015. PMID: 26621601
-
Empowering self-renewal and differentiation: the role of mitochondria in stem cells.J Mol Med (Berl). 2010 Oct;88(10):981-6. doi: 10.1007/s00109-010-0678-2. Epub 2010 Sep 1. J Mol Med (Berl). 2010. PMID: 20809088 Free PMC article. Review.
-
Gross mosaic pattern of mitochondrial DNA deletions in skeletal muscle tissues of an individual adult human subject.Biochem Biophys Res Commun. 1997 Apr 7;233(1):56-60. doi: 10.1006/bbrc.1997.6400. Biochem Biophys Res Commun. 1997. PMID: 9144395
-
Long-term analysis of differentiation in human myoblasts repopulated with mitochondria harboring mtDNA mutations.Biochem Biophys Res Commun. 1999 Dec 9;266(1):179-86. doi: 10.1006/bbrc.1999.1758. Biochem Biophys Res Commun. 1999. PMID: 10581186
-
The generation of mitochondrial DNA large-scale deletions in human cells.J Hum Genet. 2011 Oct;56(10):689-94. doi: 10.1038/jhg.2011.97. Epub 2011 Aug 25. J Hum Genet. 2011. PMID: 21866113 Review.
Cited by 8 articles
-
Random Mutagenesis, Clonal Events, and Embryonic or Somatic Origin Determine the mtDNA Variant Type and Load in Human Pluripotent Stem Cells.Stem Cell Reports. 2018 Jul 10;11(1):102-114. doi: 10.1016/j.stemcr.2018.05.007. Epub 2018 Jun 14. Stem Cell Reports. 2018. PMID: 29910126 Free PMC article.
-
Digital PCR methods improve detection sensitivity and measurement precision of low abundance mtDNA deletions.Sci Rep. 2016 Apr 28;6:25186. doi: 10.1038/srep25186. Sci Rep. 2016. PMID: 27122135 Free PMC article.
-
Achilles' heel of pluripotent stem cells: genetic, genomic and epigenetic variations during prolonged culture.Cell Mol Life Sci. 2016 Jul;73(13):2453-66. doi: 10.1007/s00018-016-2171-8. Epub 2016 Mar 9. Cell Mol Life Sci. 2016. PMID: 26961132 Review.
-
Barth Syndrome: From Mitochondrial Dysfunctions Associated with Aberrant Production of Reactive Oxygen Species to Pluripotent Stem Cell Studies.Front Genet. 2016 Jan 20;6:359. doi: 10.3389/fgene.2015.00359. eCollection 2015. Front Genet. 2016. PMID: 26834781 Free PMC article. Review.
-
Human iPS Cell-Derived Germ Cells: Current Status and Clinical Potential.J Clin Med. 2014 Oct 13;3(4):1064-83. doi: 10.3390/jcm3041064. J Clin Med. 2014. PMID: 26237592 Free PMC article. Review.
References
Publication types
MeSH terms
Substances
LinkOut - more resources
-
Full Text Sources
-
Other Literature Sources