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Observational Study
. 2018 Jun;26(2):87-91.
doi: 10.21101/cejph.a4764.

Mortality rate of ICU patients with the Middle East Respiratory Syndrome - Coronavirus infection at King Fahad Hospital, Jeddah, Saudi Arabia

Mohammed A Garout  1 , Hani A A Jokhdar  1 , Imad A Aljahdali  1 , Ahmed R Zein  2 , Reda A Goweda  1   3 , Abdurahman Hassan-Hussein  1
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Observational Study

Mortality rate of ICU patients with the Middle East Respiratory Syndrome - Coronavirus infection at King Fahad Hospital, Jeddah, Saudi Arabia

Mohammed A Garout et al. Cent Eur J Public Health. .
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Abstract

Objective: The Middle East Respiratory Syndrome Coronavirus (MERS-CoV) is a novel coronavirus circulating in the Arabian Peninsula since September 2012. It leads to significant respiratory disease and among patients with co-morbidities is associated with high mortality. This research studied the mortality rate of MERS-CoV among intensive care unit (ICU) patients and the correlation of mortality with different co-morbidities.

Methods: This was a retrospective observational study conducted at the Intensive Care Unit of the King Fahad Hospital, Jeddah, Saudi Arabia. Data was obtained through patient chart review.

Results: The total sample consisted of 52 laboratory-confirmed MERS-CoV infection patients. 39 patients died, with a 75% case-fatality rate. Many patients had underlying co-morbidities, including diabetes mellitus (51.9%), hypertension (46.2%), and chronic renal disease (21.2%).

Conclusions: MERS-CoV ICU mortality remains markedly high due to a combination of factors; the disease process of MERS-CoV leads to multiple organ failure, particularly respiratory and renal failure.

Keywords: Middle East Respiratory Syndrome Coronavirus; Saudi Arabia; intensive care units; mortality.

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