Latest Research

Quantum error correction of Gottesman–Kitaev–Preskill code states is realized experimentally in a superconducting quantum device.

A superconducting diode that has zero resistance in only one direction is realized in an artificially engineered superlattice without inversion symmetry, enabling directional charge transport without energy loss.

Observations of a cold molecular gas associated with the atomic hydrogen outflow from the centre of our Galaxy indicate that this gas has a surprisingly high mass but unclear origin.

Under high pressure, elemental sulfur shows a sharp density discontinuity that evolves with pressure and temperature and terminates at a critical point, indicating a first-order liquid–liquid phase transition.

Each one of the complete set of 118 neuron classes in Caenorhabditis elegans can be specified individually by the expression of unique combinations of homeodomain proteins.

The PAT complex, an intermembrane chaperone complex comprising the ER-resident membrane proteins CCDC47 and Asterix, directly interacts with nascent transmembrane domains to facilitate the biogenesis of multi-spanning membrane proteins.

Metabolically-mature human islet-like organoids generated from induced pluripotent stem cells are able to recapitulate insulin-responsive pancreatic islet function and avoid immunologic cell death in diabetic mouse transplantation models.

A genome-wide association study shows that myocardial trabeculae are an important determinant of cardiac performance in the adult heart, identifies conserved pathways that regulate structural complexity and reveals the influence of trabeculae on the susceptibility to cardiovascular disease.

Studies of mice and humans suggest a role for loss of the C9orf72 protein in some neurodegenerative disorders: with reduced C9orf72 levels, there is more inflammation mediated by the STING protein in immune and brain cells.

Observed global-mean sea-level rise since 1900 is reconciled with estimates based on the contributing processes, revealing budget closure within uncertainties and showing ice-mass loss from glaciers as a dominant contributor.

Single-cell RNA-sequencing analysis of embryogenesis and X chromosome inactivation in the opossum (Monodelphis domestica) resolves the developmental trajectory of a marsupial, and sheds light on the evolution of embryogenesis in mammals.

Ageing in humans is associated with an increase in circulating methylmalonic acid, which induces expression of SOX4 and promotes tumour progression.

Modelled supply curves show that, with policy reform and technological innovation, the production of food from the sea may increase sustainably, perhaps supplying 25% of the increase in demand for meat products by 2050.

Structural studies of the dimerization quality control E3 ubiquitin ligase SCF–FBXL17 indicate that its selectivity for aberrant complex formation is based on recognizing both shape and complementarity of interacting domains.

A direct ink writing protocol for silica aerogels enables 3D printing of lightweight, miniaturized objects with complex shapes, with the possibility to easily add functionality by incorporating nanoparticles.

Melanoma cells undergo less oxidative stress and less ferroptosis in lymph than in blood, owing to higher levels of oleic acid in lymph, and thus exposure to the lymphatic environment increases subsequent metastasis through blood.

A built-in electric field at the interface of metals and centrosymmetric semiconductors is shown to induce polar structures in the semiconductors and generate substantial piezoelectric and pyroelectric effects.

Reconstitution of the activation of the MLH1–MLH3 endonuclease shows how crossovers are formed during meiosis.

An iron complex sequentially activates N₂ and C–H bonds in benzene to form aniline, with coupling achieved through partial silylation of a reduced iron–nitrogen complex and phenyl migration.

Structural determination of the salicylic-acid-binding core of Arabidopsis NPR4 sheds light on the mechanisms through which this plant hormone interacts with its receptors, providing insights that are of potential use in engineering enhanced immunity.

Structural and physiological studies show that the inner membrane protein PbgA is a crucial sensor of lipopolysaccharide (LPS) and regulates the activity of the LPS biosynthesis enzyme LpxC.

4-Vinylanisole, which is emitted by gregarious locusts or as a result of aggregation of solitary locusts, is identified as an aggregation pheromone that strongly attracts both solitary and gregarious locusts, acting via the olfactory receptor OR35.

Buckled monolayer graphene superlattices are found to provide an alternative to twisted bilayer graphene for the study of flat bands and correlated states in a carbon-based material.

Retinal pericytes connect via interpericyte tunnelling nanotubes into functional syncytia that regulate microcirculatory blood flow to help to match local blood flow with neuronal activity.

A strongly lensed galaxy at redshift 4.2 appears to be a dynamically cold disk galaxy, similar to spiral galaxies in the local neighbourhood and weakly affected by extreme physical processes.

In xenograft tumour models in mice, modulation of dietary serine, serine palmitoyltransferase or phosphoglycerate dehydrogenase activity enables control of the endogenous synthesis of deoxysphingolipids, sensitizing the tumours to metabolic stress and slowing their progression.

Conventional type 1 dendritic cells perform antigen processing and priming of CD4⁺ and CD8⁺ T cells against tumour antigens, orchestrating their cross-talk to effect anti-tumour immunity.

High-quality rhombohedral graphite films are found to offer an alternative to twisted bilayer graphene as a platform for studying correlated physics in carbon materials.

A qubit generated and stabilized in a superconducting microwave resonator by encoding it into Schrödinger cat states produced by Kerr nonlinearity and single-mode squeezing shows intrinsic robustness to phase-flip errors.

When tropical forest soils are warmed in situ, they release more CO₂ than predicted by theory, creating a potentially substantial positive feedback to climate change.