Acne is the most common of all skin conditions. It affects people across several age groups, from adolescence to middle age.
A strong family history is usually present in acne patients. Many school-going children with acne have parents or siblings who had/have acne.
A study on acne in twins in the US showed that both twins had a high risk of inheriting acne. This was reported again in an Australian study involving adolescent twins.
[P]revious studies showed a heritability estimate ranging from 50-90% for acne. In other words, approximately 50-90% of acne was due to genetic variation in the affected individuals.
A large UK study involving 400 twin pairs showed that 81% of acne was due to genetic factors.
Up to 47% of twins with acne had at least one sibling with acne. In contrast, only 15% of twins without acne reported having another sibling who had acne…[T]he transmission of acne was also studied, with 41% of twins with acne having one or more children who also had acne. Only 17% of twins without acne had children suffering from the condition.
It is noteworthy that individuals with a history of severe teenage acne have a higher risk of prostate and breast cancer.
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